Prof. Dr. Mümtaz İŞCAN

CURRICULUM VITAE

  • Ankara Eczacılık (Undergrad , 1975)
  • Ankara Toxicology (Phd , 1982)
  • The investigation of the effects of nickel on mouse liver mixed function oxidase enzyme system
  • Interindividual variability of coumarin 7-hydroxylation in a Turkish population.
  • Investigation of lipid peroxidation levels in breast tumors
  • Investigation of the ethoxyresorufin O-deethylase enzyme activity in breast cancer
  • The effects of cadmium and nickel on rat testis xenobiotic metabolism
  • The clinical significance of interactions of warfarin, carbamazepin and amitriptilin interaction at metabolism level
  • The role of metabolic (GSTP1) polymorphism in lung cancer
  • The interactions of calcium channel blokers at metabolism level and the importance of CYP3A4
  • The role of metabolic (CYP1) polymorphism in drug resistance in lung cancer
  • The investigation of the GSTP1 gene polymorphism in some individuals of Turkish population
  • The investigation of the GST Omega 1 (A140D) gene polymorphism in some individuals of Turkish population
  • The role of metabolic (CYP1B1) polymorphism in drug resistance in lung cancer
  • The role of metabolic (CYP3A4) polymorphism in drug resistance in lung cancer
  • The investigation of the effects of cigarette smole on rat liver and lung xenobiotic metabolizing enzymes
  • The investigation of the antioxidant enzymes in breast carcinomas
  • The investigation of the role of metabolic polymorphism on the individual sensitivity to polycyclic aromatic hydrocarbons
  • The role of metabolic polymorphism in drug resistance in lung cancer
  • The role of metabolic (CYP2E1) polymorphism in drug resistance in lung cancer
  • The role of metabolic (mEH) polymorphism in drug resistance in lung cancer
  • Assessment of the serum periostin, tenascin-C, eopterin, YKL-40 and indolamin levels in asbest related malign mesotelioma
  • The investigation of the effects of nickel on mouse liver mixed function oxidase enzyme system 1987
  • The investigation of the effects of cigarette smole on rat liver and lung xenobiotic metabolizing enzymes 1987
  • The combined effects of cadmium and nickel on rat and guinea pig monoxygenases and glutathione conjugation enzymes 1990
  • The monitoring of the Van lake pollution by measuring fish cytochrome P-450 and glutathione S transferase enzyme activites as biological indicator. 1997
  • The role of EROD activity in development of human breast cancer related with chemical carcinogens 1997
  • The investigation of the expression and localization of CYP1A1 and CYP1B1 which play role in development of breast cancer in normal and neoplastic breast tissue cells 1998
  • The investigation of the role of metabolic polymorphism on the individual sensitivity to polycyclic aromatic hydrocarbons 2001
  • The role of metabolic (GSTP1) polymorphism in drug resistance in lung cancer 2006
  • The role of metabolic (CYP1) polymorphism in drug resistance in lung cancer 2007
  • The investigation of the GST Omega 1 (A140D) gene polymorphism in some individuals of Turkish population 2008
  • The role of metabolic (CYP2E1) polymorphism in drug resistance in lung cancer 2010
  • The role of metabolic (CYP1B1) polymorphism in drug resistance in lung cancer 2015
  • he role of metabolic (CYP3A4) polymorphism in drug resistance in lung cancer 2017
  • Assessment of the serum periostin, tenascin-C, eopterin, YKL-40 and indolamin levels in asbest related malign mesotelioma. 2019
  • The investigation of the activites of antioxidant enzymes in breast carcinomas 1992
  • The effects of benzimidazol compounds having retinodial acitivity on free radicals and lipid peroxidation 1996
  • The role of EROD (CYP1A1) enzyme activity on human breast cancer 1997
  • The investigation of the combined effects of cadmium and nickel on rat lung and kidney cytochrome P450 enzyme system which play role in bioactivation of xenobiotics 1998
  • Turkish Scientific and Technical Research Council (TUBITAK) Incentive Award in Medical Sciences 1991
  • SEDAT SİMAVI FOUNDATION AWARD IN HEALTH SCIENCES 1993
  • ANKARA UNIVERSITY INCENTIVE AWARD IN HEALTH SCIENCES 1997
  • Molecular Toxicology
  • Risk Assessment of chemicals
  • Head of the Department of Toxicology, Faculty of Pharmacy, Ankara University 2003-2009