Mustafa	IŞIN

Assoc. Prof. Dr. MUSTAFA IŞIN

Faculty of Medicine

Telephone number +90 392 671 11 11
Extension 2553
Office MD201
Other information

CURRICULUM VITAE

Education
  • Istanbul Üniversitesi Institute of Health Sciences (PhD, 2009)
  • Istanbul Üniversitesi Institute of Health Sciences (Master, 2002)
  • Hacettepe Üniversitesi Faculty of Science (Undergraduate, 1998)
Publications

Articles published in peer reviewed international journals (SCI,SSCI,Arts and Humanities)

  • Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T, Archer F, Atkin-Smith GK, Ayre DC, Bach JM, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Benmoussa A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borràs FE, Bosch S, Boulanger CM, Breakefield X, Breglio AM, Brennan MÁ, Brigstock DR, Brisson A, Broekman ML, Bromberg JF, Bryl-Górecka P, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Buzás EI, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FA, Coyle B, Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Santana EF, De Wever O, Del Portillo HA, Demaret T, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominguez Rubio AP, Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, Ekström K, El Andaloussi S, Elie-Caille C, Erdbrügger U, Falcón-Pérez JM, Fatima F, Fish JE, Flores-Bellver M, Försönits A, Frelet-Barrand A, Fricke F, Fuhrmann G, Gabrielsson S, Gámez-Valero A, Gardiner C, Gärtner K, Gaudin R, Gho YS, Giebel B, Gilbert C, Gimona M, Giusti I, Goberdhan DC, Görgens A, Gorski SM, Greening DW, Gross JC, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P, Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AG, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L, Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khomyakova E, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ 2nd, Kornek M, Kosanović MM, Kovács ÁF, Krämer-Albers EM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Kuypers S, Laitinen S, Langevin SM, Languino LR, Lannigan J, Lässer C, Laurent LC, Lavieu G, Lázaro-Ibáñez E, Le Lay S, Lee MS, Lee YXF, Lemos DS, Lenassi M, Leszczynska A, Li IT, Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Linē A, Linnemannstöns K, Llorente A, Lombard CA, Lorenowicz MJ, Lörincz ÁM, Lötvall J, Lovett J, Lowry MC, Loyer X, Lu Q, Lukomska B, Lunavat TR, Maas SL, Malhi H, Marcilla A, Mariani J, Mariscal J, Martens-Uzunova ES, Martin-Jaular L, Martinez MC, Martins VR, Mathieu M, Mathivanan S, Maugeri M, McGinnis LK, McVey MJ, Meckes DG Jr, Meehan KL, Mertens I, Minciacchi VR, Möller A, Møller Jørgensen M, Morales-Kastresana A, Morhayim J, Mullier F, Muraca M, Musante L, Mussack V, Muth DC, Myburgh KH, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri C, Neri T, Nieuwland R, Nimrichter L, Nolan JP, Nolte-'t Hoen EN, Noren Hooten N, O'Driscoll L, O'Grady T, O'Loghlen A, Ochiya T, Olivier M, Ortiz A, Ortiz LA, Osteikoetxea X, Østergaard O, Ostrowski M, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Phinney DG, Pieters BC, Pink RC, Pisetsky DS, Pogge von Strandmann E, Polakovicova I, Poon IK, Powell BH, Prada I, Pulliam L, Quesenberry P, Radeghieri A, Raffai RL, Raimondo S, Rak J, Ramirez MI, Raposo G, Rayyan MS, Regev-Rudzki N, Ricklefs FL, Robbins PD, Roberts DD, Rodrigues SC, Rohde E, Rome S, Rouschop KM, Rughetti A, Russell AE, Saá P, Sahoo S, Salas-Huenuleo E, Sánchez C, Saugstad JA, Saul MJ, Schiffelers RM, Schneider R, Schøyen TH, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke GV, Shetty AK, Shiba K, Siljander PR, Silva AM, Skowronek A, Snyder OL 2nd, Soares RP, Sódar BW, Soekmadji C, Sotillo J, Stahl PD, Stoorvogel W, Stott SL, Strasser EF, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh WS, Tomasini R, Torrecilhas AC, Tosar JP, Toxavidis V, Urbanelli L, Vader P, van Balkom BW, van der Grein SG, Van Deun J, van Herwijnen MJ, Van Keuren-Jensen K, van Niel G, van Royen ME, van Wijnen AJ, Vasconcelos MH, Vechetti IJ Jr, Veit TD, Vella LJ, Velot É, Verweij FJ, Vestad B, Viñas JL, Visnovitz T, Vukman KV, Wahlgren J, Watson DC, Wauben MH, Weaver A, Webber JP, Weber V, Wehman AM, Weiss DJ, Welsh JA, Wendt S, Wheelock AM, Wiener Z, Witte L, Wolfram J, Xagorari A, Xander P, Xu J, Yan X, Yáñez-Mó M, Yin H, Yuana Y, Zappulli V, Zarubova J, Žėkas V, Zhang JY, Zhao Z, Zheng L, Zheutlin AR, Zickler AM, Zimmermann P, Zivkovic AM, Zocco D, Zuba-Surma EK. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018 Nov 23;7(1):1535750. doi: 10.1080/20013078.2018.1535750. - 2018
  • Fayda M, Isin M, Tambas M, Guveli M, Meral R, Altun M, Sahin D, Ozkan G, Sanli Y, Isin H, Ozgur E, Gezer U. Do circulating long non-coding RNAs (lncRNAs) (LincRNA-p21, GAS 5, HOTAIR) predict the treatment response in patients with head and neck cancer treated with chemoradiotherapy? Tumour Biol. 2016 Mar;37(3):3969-78. doi: 10.1007/s13277-015-4189-1. - 2016
  • Işın M, Uysaler E, Özgür E, Köseoğlu H, Şanlı Ö, Yücel ÖB, Gezer U, Dalay N. Exosomal lncRNA-p21 levels may help to distinguish prostate cancer from benign disease. Front Genet. 2015 May 6;6:168. doi:10.3389/fgene.2015.00168. - 2015
  • Isin M, Dalay N. LncRNAs and neoplasia. Clin Chim Acta. 2015 Apr 15;444:280-8. doi: 10.1016/j.cca.2015.02.046. - 2015
  • Gezer U, Özgür E, Cetinkaya M, Isin M, Dalay N. Long non-coding RNAs with low expression levels in cells are enriched in secreted exosomes. Cell Biol Int. 2014 Sep;38(9):1076-9. doi: 10.1002/cbin.10301. - 2014
  • Isin M, Ozgur E, Cetin G, Erten N, Aktan M, Gezer U, Dalay N. Investigation of circulating lncRNAs in B-cell neoplasms. Clin Chim Acta. 2014 Apr 20;431:255-9. doi: 10.1016/j.cca.2014.02.010. - 2014
  • Özgür E, Mert U, Isin M, Okutan M, Dalay N, Gezer U. Differential expression of long non-coding RNAs during genotoxic stress-induced apoptosis in HeLa and MCF-7 cells. Clin Exp Med. 2013 May;13(2):119-26. doi:10.1007/s10238-012-0181-x. - 2013
  • Isin M, Yenerel M, Aktan M, Buyru N, Dalay N. Analysis of p53 tumor suppressor pathway genes in chronic lymphocytic leukemia. DNA Cell Biol. 2012 May;31(5):777-82. doi: 10.1089/dna.2011.1314. - 2011
  • Buyru N, Altinisik J, Isin M, Dalay N. p53 codon 72 polymorphism and HPV status in lung cancer. Med Sci Monit. 2008 Sep;14(9):CR493-7. - 2008

Papers presented in National conferences and printed as proceedings

  • ISIN HÜSNIYE,ISIN MUSTAFA,TALU CANAN KELTEN,TRABULUS DIDEM CAN,KARAÇETIN DIDEM,AKSOY SEFIKA,DALAY NEJAT (2017). Meme Kanserli Hastalarda WRN ve DSP Genlerinin Arastırılması. XV. Tıbbi Biyoloji ve Genetik Kongresi, 118-118. - 2017
  • Isın Hüsniye,ISIN MUSTAFA,Talu Canan Kelten,Trabulus Didem Can,Karaçetin Didem,Aksoy Sefika,Dalay Nejat (2015). Meme Kanserli Hastalarda WRN ve DSP Genlerinde GenIfadesi ve Metillenme Degisikliklerinin Arastırılması. XIV. Ulusal Tıbbi Biyoloji ve Genetik Kongresi, 121-122. - 2015
  • ISIN MUSTAFA,Isın Hüsniye,Talu Canan Kelten,Trabulus Didem,Karaçetin Didem,Dalay Nejat (2015). Meme Kanserinde GATA3 ve miRNA29b IfadelerininArastırılması. XIV. Ulusal Tıbbi Biyoloji ve Genetik Kongresi, 197-198. - 2015
  • ÖZGÜR EMRE,Mert Ufuk,ISIN MUSTAFA,GEZER UGUR,DALAY MEHMET NEJAT (2011). Genotoksik Stres Ilintili Apoptozda Kodlanmayan RNA Analizi. XII. Tıbbi Biyoloji ve Genetik Kongresi Antalya, 31(6), 42-42. - 2011
  • Mert Ufuk,ÜSTEK DURAN,ÖZGÜR EMRE,ISIN MUSTAFA,DALAY MEHMET NEJAT,GEZER UGUR (2011). Kan Plazmasında H3K9me3 Ilintili Nükleozomal DNA nın Yeni Dizileme Yöntemiyle Karakterizasyonu. XII. Ulusal Tıbbi Biyoloji ve Genetik Kongresi Antalya, 31(6), 36-36. - 2011
  • ISIN MUSTAFA,AKTAN MELIH,BUYRU AYSE NUR,DALAY MEHMET NEJAT (2011). Kronik Lenfositik Lösemili Hastalarda P53 Geni Ekzon 6 Degisikliklerinin Incelenmesi. 19. Ulusal Kanser Kongresi, 482-482. - 2011
  • ISIN MUSTAFA,YENEREL MUSTAFA NURI,AKTAN MELIH,BUYRU AYSE NUR,DALAY MEHMET NEJAT (2009). Kronik Lenfositik Lösemili Hastalarda p53 P14ARF ve HDM2 Gen Ifade Düzeyleri. XVIII. Ulusal Kanser Kongresi, Antalya - 2009
  • Beser Aslı Rehber,ISIN MUSTAFA,BASARAN MERT,DALAY MEHMET NEJAT (2007). Von Hippel LIndau Ailesinin Genetik Açıdan Incelenmesi. XVII. Ulusal Kanser Kongresi, Antalya - 2007
  • ISIN MUSTAFA,DALAY MEHMET NEJAT (2003). Akut ve Kronik Miyeloid Lösemili Hastalarda p53 Kodon 72 Polimorfizmlerinin Arastırılması. XV. Ulusal Kanser Kongresi, Kemer-Antalya - 2003

Papers presented in international conferences and printed as proceedings

  • ISIN MUSTAFA,Isın Hüsniye,Talu Canan Kelten,Trabulus Didem,Karaçetin Didem,Dalay Nejat (2015). Involvment of miRNA29b in breast cancer. MicroRNAs and Noncoding RNAs in Cancer, 49-49. - 2015
  • ISIN MUSTAFA (2013). Exosomal lncRNA Levels may Help Discriminate Prostate Cancer from Bening Disease. 8th International Conference on Circulating Nucleic Acids in Plasma and Serum. 7-8 Kasım, Baltimore-Maryland, A.B.D., 61-61. - 2013
  • ISIN MUSTAFA,Fayda Merdan,Güveli Murat,Tambas Makbule,GEZER UGUR,MERAL RASIM,DALAY MEHMET NEJAT (2013). Circulating Long Non Coding RNA HOTAIR GAS5 and LincRNA p 21 Levels in Patients with Nasopharyngeal Cancer vs Other Inoperable Head and Neck Squamous Cell Cancer. 6th International Symposium on NAsopharyngeal Carcinoma - 2013
  • Dalay Nejat,ISIN MUSTAFA,ÇETIN GÜVEN,AKTAN MELIH (2013). Analysis of gene copy number changes in chronic lymphocytic leukemia. Chromatin and Epigenetics in Cancer, 73(13 Supplement), 60-60., Doi: 10.1158/1538-7445.CEC13-A60 - 2013
  • ISIN MUSTAFA,ÖZGÜR EMRE,ERTEN SEBILE NILGÜN,GEZER UGUR,DALAY MEHMET NEJAT (2012). Expression levels of circulating gas5 and lincrna p21 in multiple myeloma. 40th Congress of the International-Society-of-Oncology-and-Biomarkers Kudüs-Israil, 33, 111-111. - 2012
  • ISIN MUSTAFA,ÖZGÜR EMRE,AKTAN MELIH,GEZER UGUR,DALAY MEHMET NEJAT (2011). Investigation of lncRNAs in Chronic Lymphocytic Leukemia and Prostate Cancer. 7th NCRI Cancer Conferance 6-9 Kasım 2011, BT Convention Center, Liverpool, Ingiltere - 2011
  • ISIN MUSTAFA,ÖZGÜR EMRE, AKTAN MELIH,ERTEN SEBILE NILGÜN,GEZER UGUR,DALAY MEHMET NEJAT (2011). Investigation of plasma lncRNA levels in chronic lymphocytic leukemia and multiple myeloma patients. 7th International Conference on Circulating Nucleic Acids in Plasma and Serum, 2(1), 32-21. - 2011
  • ISIN MUSTAFA,YENEREL MUSTAFA NURI,AKTAN MELIH,BUYRU AYSE NUR,DALAY MEHMET NEJAT (2010). ZBTB7A and BCL6 Genes are not Expressed in CLL. Meeting of the International Society of Oncology and BioMarkers (ISOBM), 31(1), 96-96. - 2010

Articles published in other peer reviewed international journals

  • Yazici H, Zipprich J, Peng T, Akisik EZ, Tigli H, Isin M, Akisik EE, Terry MB, Senie RT, Li L, Peng M, Liu Z, Dalay N, Santella RM. Investigation of the miR16-1 (C > T) + 7 Substitution in Seven Different Types of Cancer from Three Ethnic Groups. J Oncol. 2009;2009:827532. doi: 10.1155/2009/827532. - 2009
  • Işin M., Müslümanoğlu M.E., Bozfakioğlu Y., İğci A., Dalay M.N., "Lack of Expresion of Epstein-Barr and Human Papillomavirus Gene Products in Breast Cancer", JOURNAL OF TUMOR MARKER ONCOLOGY, vol.19, pp.331-335, 2004 - 2004
Awards
  • TROD Prof. Dr. Nijad Bilge Award, Turkish Radiation Oncologists Association (2017)
  • 5. Onkoloji Enstitüsü Çalıstayı Akademik Çalısma Ödülü, ISTANBUL UNIVERSITY (2014)
Research Areas
  • ncRNA
  • Molecular Oncology
  • Medical Biology and Genetics