CIU-Ender-Volkan

Asst. Prof. Dr. ENDER VOLKAN

Faculty of Arts and Sciences

Telephone number +90 392 671 11 11
Extension 2652
Office ST252
Other information

CURRICULUM VITAE

Education
  • Washington University in St. Louis PhD in Molecular Microbiology and Microbial Pathogenesis (PhD, 2013)
  • University of Missouri-Kansas City BSc in Biology (Major), Chemistry (Minor) (Undergraduate, 2006)
Publications

Articles published in peer reviewed international journals (SCI,SSCI,Arts and Humanities)

  • Comparison of SARS-CoV-2 anti-spike receptor binding domain IgG antibody responses after CoronaVac, BNT162b2, ChAdOx1 COVID-19 vaccines, and a single booster dose: a prospective, longitudinal population-based study - 2022
  • COVID-19: Structural Considerations for Virus Pathogenesis, Therapeutic Strategies and Vaccine Design in the Novel SARS-CoV-2 Variants Era - 2021
  • Allium willeanum Holmboe exerts anticancer activities on metastatic breast cancer cells MCF-7 and MDA-MB-231 - 2021
  • Under the COVID-19 Lockdown: Rapid Review About the Unique Case of North Cyprus - 2021
  • Volkan, E., & Volkan, E. (2020). Under the COVID-19 lockdown: Rapid review about the unique case of North Cyprus. Psychological Trauma: Theory, Research, Practice, and Policy, 12(5), 539-541. http://dx.doi.org/10.1037/tra0000809 - 2020
  • O Isbilen, N Rizaner, E Volkan. Anti-proliferative and cytotoxic activities of Allium autumnale P. H. Davis (Amaryllidaceae) on human breast cancer cell lines MCF-7 and MDA-MB-231. BMC Complementary and Alternative Medicine. 2018; 18 (30), 1-13 - 2018
  • Thieng Pham, Nadine S. Henderson, Gilles Phan, Ender Volkan, Scott Hultgren, Gabriel Waksman, David G. Thanassi, Anne H. Delcour, 'Electrophysiological Analysis of PapC Mutants Provides Insights into the Mechanism of Plug Displacement' (2014), Biophysical Journal. 01/2014; 106(2):557a. DOI: 10.1016/j.bpj.2013.11.3098 - 2013
  • Volkan, E, Kalas V, Pinkner JS, Dodson KW, Henderson NS, Pham T, Waksman G, Delcour AH, Thanassi DG, Hultgren SJ., (2013), 'Molecular Basis of Usher Pore Gating in Escherichia coli Pilus Biogenesis.' , Proc Natl Acad Sci U S A, 110(51):20741-6. - 2013
  • Volkan, E., Ford B, Pinkner, J., Dodson, K., Henderson, N., Thanassi, D., Waksman, G., Hultgren, S., (2012). "Domain activities of PapC usher reveal the mechanism of action of an Escherichia coli molecular machine." Proc Natl Acad Sci U S A 109(24): 9563-9568. - 2012
  • Ford, B., Verger, D., Dodson, K., Volkan, E., Kostakioti, M., Elam, J., Pinkner, J., Waksman, G., Hultgren, S., (2012). "The Structure of the PapD-PapGII Pilin Complex Reveals an Open and Flexible P5 Pocket." J Bacteriol 194(23): 6390-6397 - 2012
  • Phan G, Remaut H, Wang T, Allen W, Pirker K, Lebedev A, Henderson N, Geibel S, Volkan E, Yan J, Kunze M, Pinkner J, Ford B, Kay C, Li H, Hultgren S, Thanassi D, Waksman G, (2011). 'Crystal structure of the FimD usher bound to its cognate FimC-FimH substrate." Nature 474(7349): 49-53 - 2011

Books and books chapters published internationally

  • Allium Species in the Fight Against Cancer, Isbilen, O; Volkan, E; Cancer Therapy, MedDocs Publishers, 2020, ISBN 978-81-936678-8-0 - 2020
  • Volkan, E., Kalas,V.,Hultgren, S.,'Pili and Fimbriae of Gram-Negative Bacteria', Molecular Medical Microbiology, 2nd Edition, 147-162, Elsevier Science, Nov 26, 2014. - 2014
  • Kalas,V.*, Volkan, E.*, Hultgren, S., 'Adhesive pili of the Chaperone-Usher Pathway' Escherichia coli, Pathotypes and Principles of Pathogenesis 2e, 361-387, Elsevier Science, Aug 5, 2013. - 2013
  • Microbiological approaches to Treating Cancer E Volkan, O Isbilen Cancer Therapy, 1-7, Meddocs Publisher

Articles published in National journals

  • Anticancer Activities of Allium sativum L. Against MCF-7 and MDA-MB-231 Breast Cancer Cell Lines Mediated by Caspase-3 and Caspase-9 - 2020
  • Djamgoz MBA, Akun E, Arslan B, Onbaşı R, İşbilen Ö, Kavaz D, Volkan E, Rizaner N. Cancer in North Cyprus: 2. Biomedical Research Activities.Cyprus J Med Sci 2017; 2: 13-18 - 2017

Papers presented in international conferences and printed as proceedings

  • In vitro anticancer activity of Allium sativum L. against MCF-7 and MDA-MB-231 human breast cancer cell lines via caspase-3 and caspase-9 mediated pathway, WOCMAP 2019, Ovgu Isbilen , Ender Volkan - 2019
  • Allium willeanum Holmboe exhibits in vitro antimetastatic, antiproliferative activities in a caspase-3 and caspase- 9 mediated manner on human breast cancer cell lines, WOCMAP 2019, Ovgu Isbilen , Ender Volkan - 2019
  • Antimicrobial and Biofilm Inhibitory Activities of Allium orientale Boiss on Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli, WOCMAP 2019, Ovgu Isbilen , Ender Volkan - 2019
  • Pham T., Henderson N., Phan G., Volkan E., Hultgren S., Waksman, G., Thanassi, D., Delcour A., Electrophysiological Analysis of PapC Mutants Provides Insights into the Mechanism of Plug Displacement, Biophysical Society Annual Meeting, San Francisco, CA, 2014. - 2014
  • Volkan E., et al., Novel activities of isolated domains revel the mechanisms of action of PapC Usher. ASM General Meeting, Convention Center, San Francisco, CA, 2012. - 2012
  • Volkan E., et al., Usher pore gating and Uropathogenic E. Coli Pilus Biogenesis. ASM General Meeting, Convention Center, New Orleans, LA, 2011. - 2011
  • Volkan, E., et al. PapD Revisited: An investigation of conserved surfaces of the periplasmic chaperone of P pili in Uropathogenic E. coli leads to observed molecular mimicry with the C terminal domain of the usher PapC. ASM General Meeting, Convention Center, San Diego, CA, 2010. - 2010
  • Volkan, E., et al. PapD Revisited: An investigation of conserved surfaces of the periplasmic chaperone of P pili in Uropathogenic E. coli leads to observed molecular mimicry with the C terminal domain of the usher PapC. Midwest Microbial Pathogenesis Conference, Saint Louis, MO, USA, 2010. - 2010

Papers presented in National conferences and printed as proceedings

  • Samarkina, A., van Eyssen, S., Volkan, E, 'Differential Anticancer Effects of Scytosiphon Lomentaria and Zostera Marina on Human Breast Cancer Adenocarcinoma MDA-MB-231 and MCF-7 Cell Lines', International Muldtidisciplinary Symposium on Drug Research and Development (IMSDRD), 2015, Eskişehir, Turkey - 2015
  • Samarkina, A., van Eyssen, S., Volkan, E., 'Toxicity, Adhesion and Invasion of Highly and Lowly Metastatic Human Breast Cancer Cells by Uropathogenic Escherichia coli UTI-89 Strain', International Muldtidisciplinary Symposium on Drug Research and Development (IMSDRD), 2015, Eskişehir, Turkey - 2015
  • Volkan, E., Hultgren, S., 'Chaperone-Usher Pilus Assembly Mechanisms and Antivirulence Therapeutics', Fourth International Meeting on Pharmacy & Pharmaceutical Sciences, Istanbul, Turkey, 2014. - 2014
  • Zeden,M.S., Hultgren, S. Volkan, E.,, 'Pros and Cons of Pilus: A target for Antivirulence Therapeutics and and Unlikely Player in the Fight Against Cancer', Fourth International Meeting on Pharmacy & Pharmaceutical Sciences, Istanbul, Turkey, 2014. - 2014
  • Zeden,M.S.,. Volkan, E.,, 'Specific Killing of Highly Metastatic Breast Cancer Cells by Type 1 Piliated Escherichia coli', Fourth International Meeting on Pharmacy & Pharmaceutical Sciences, Istanbul, Turkey, 2014. - 2014
  • Zeden,M.S., Hultgren, S. Volkan, E.,, 'Pros and Cons of Pilus: A target for Antivirulence Therapeutics and and Unlikely Player in the Fight Against Cancer', 17th International Pharmaceutical Technology Symposium (IPTS), Antalya, Turkey, 2014 - 2014

Other Publications

  • Volkan, E., 'Lejyoner Hastalığına Dikkat', Halkın Sesi Gazetes, 20 Mayıs 2015 - 2015
Thesis Supervision

Master Thesis Supervised

  • Alternative Therapies and Antivirulence Factors for Treatment of Urinary Tract Infections- Gizem Behlül, 2016 - 2016
  • Legionella and Microbial Contamination Awareness In Cyprus: Importance of Legionella in Pharmaceutical Approaches, Complications, Treatment and Prevention Methods - Açelya Coşar, 2016 - 2016
  • Antimicrobial and Biofilm Inhibitory Activities of Allium orientale Boiss on Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli
  • The antimicrobial and anti-biofilm activity of Ficus carica L extract on pathogenic bacteria.

Doctorate Thesis Supervised

  • Anti-proliferative and cytotoxic activities of Allium autumnale P. H. Davis (Amaryllidaceae) on human breast cancer cell lines MCF-7 and MDA-MB-231.
Projects
  • Chaperone Usher Pili içeren Gram-negatif bakterilerin MDA-MB-231 yüksek metastazlı meme kanseri hücreleri ile etkileşimi.
  • Akdenizden izole edilen alg türlerinin MDA-MB-231 yüksek metastazlı meme kanseri hücreleri ile etkileşimi.
  • Pilüslü ve Pilüssüz Üropatojenik E. coli ile MDA-MB-231 yüksek metastazlı meme kanseri hücrelerinin etkileşimi.
  • KKTC kullanım sularında Legionella spp. bakterilerin tetkiki ve kontrolu.
  • Anti-proliferative and cytotoxic activities of Allium autumnale P. H. Davis (Amaryllidaceae) on human breast cancer cell lines MCF-7 and MDA-MB-231.